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Novo Nordisk said Wednesday that demand for its Wegovy pill got off to a strong start after it launched in the U.S

Gut, 65(3), 426-435

Who might benefit most

95% CI 0.25, 0.15) and GLP-1 RAs/SGLT-2is (WMD: 0.2

Dose adjustments, slower titration [dose increase] schedules, hydration strategies, nutrition counseling, and other symptom-management approaches can often help improve tolerability

Tirzepatide, another glucose-lowering medication known by the brand name Mounjaro, was approved for diabetes treatment in 2022 and is under fast-track review for weight loss
