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The result of combining both is a larger, more sustained GH pulse that neither compound produces alone, without the cortisol elevation or appetite stimulation associated with older secretagogues like GHRP-2 or GHRP-6

Koopman C, Pelletier KR, Murray JF, et al

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To identify potential neural substrates underlying tirzepatides effects, we employed electrophysiological recordings across reward-related brain regions and conducted proteomic analysis of tissue samples from alcohol-consuming rats

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