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A 2025 research letter published in JAMA Ophthalmology found liraglutide increased the risk of NAION by 25%

Gaps in treatment or abrupt dose changes can trigger rebound appetite increases, weight regain, and amplified side effects when you resume

Most patients reach stable weight loss or plateau within 46 months of therapy

The PwC analysis of Numerator data has shown an increase of 4% to 6% in apparel categories such as activewear, denim dresses and intimates for GLP-1 households, "driven by a wardrobe replacement and a move toward more form-fitting clothes to match newfound, more confident identifies," said Furman
