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However, the absence of prospective short- and long-term outcome data underscores the need for systematic investigation to define optimal timing, safety parameters, and oncologic efficacy of weight-loss interventions in this high-risk population.

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GLP-1 receptor agonists, originally developed for managing type 2 diabetes, have rapidly emerged as highly effective treatment options for obesity

AstraZeneca has begun a clinical trial in Russia of the oral drug elecoglipron, intended for the treatment of obesity and type 2 diabetes, the company's