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They work by mimicking a natural gut hormone that helps control blood sugar, slows digestion, and reduces appetite

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Retention of glucagon function is required to achieve such an advantage over GLP-1 monotherapy

Preclinical and initial human studies suggest that glucagon-like peptide-1 receptor agonists may be promising treatments for alcohol use disorder, but existing approved treatments should be used until safety and efficacy is demonstrated in clinical trials.

It explains how each works, evidence and safety differences, and practical guidance for choosing a clinician-supervised path.

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