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rather, it predicts heightened sensitivity to substrate imbalance during sustained pharmacological hypophagia

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Receptor Comparison# Weight Loss Efficacy# Retatrutide Phase 2 Results# The Phase 2 obesity trial (Jastreboff et al., NEJM 2023

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Moreover, ongoing education and training for healthcare providers regarding the benefits and limitations of GLP-1 therapies are vital

12 These benefits are smaller than the 1520% weight loss observed with GLP-1 RAs or co-agonists
