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Five case reports detail that patients receiving testosterone injections subsequently developed IIH, 4 of whom showed a temporal relationship between commencement of testosterone and symptoms of IIH (Table 1) (4246)

Kalathil stresses, This momentum presents both opportunity and urgency for pharmaceutical and device manufacturers to ensure delivery systems can keep pace with demand while maintaining safety, sustainability, and regulatory integrity. The complexity of these devices, often involving multilayer packaging, elastomeric seals, and polymeric components, also heightens the need for robust analytical validation

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