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2021;12 doi: 10.3389/fendo.2021.645563

It works by blocking 2 calcium channels and inhibiting the release of excitatory neurotransmitters from presynaptic vesicles

The effect of GIP on inflammation is controversial

In the worst scenario, you end up with medications that are potentially harmful. Some people who cant find semaglutide at their regular pharmacy have turned to compounding pharmacies, which mix or alter drug ingredients to create medications tailored to specific patient needs

It also appears to modulate the gastrointestinal side effects of GLP-1 activation, which may explain why tirzepatide is better tolerated despite being more potent

Thiara, who is also an assistant professor of clinical medicine, says some patients stick to a lower dose because they cant tolerate more GLP-1 medication, which is fine