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While it offers potential advantages such as fewer side effects, lower costs, and better adherence, the practice still requires more research to confirm its safety and effectiveness

Results of the Literature Review A total of 183 records were screened, and 76 studies were included in the final synthesis

Why it matters: Farxiga increases glucose excretion, which creates an osmotic pull that increases urine output

Although this difference approached but did not reach the threshold for clinical significance established in other studies,134 the findings suggest the potential neuroprotective effects of lixisenatide, possibly mediated by increased synaptic dopamine levels, as supported by preclinical and clinical research in addictive disorders.135,136 Further investigations are warranted to elucidate the mechanisms underlying GLP-1RAs action in PD

Retatrutide changes the equation entirely

BMC Health Serv Res 21(1):582