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Int J Life Sci Pharma Res 13(5):P25P50 Makrilakis K (2019) The role of DPP-4 inhibitors in the treatment algorithm of type 2 diabetes mellitus: when to select, what to expect

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Step therapy can be waived with documented contraindications or prior intolerance

Nausea peaks on days 1 to 3 and usually improves by day 4 or 5

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