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However, most patients who discontinue GLP-1s either maintain their weight loss or regain slowly, and the facial fat pads do not reliably replenish through weight regain alone

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With appropriate patient selection, monitoring, and medical supervision, weight loss injections can be used safely in most individuals, including many with cardiovascular risk factors or established heart disease

M., Abdelbasset, W

This led to the identification of GLP-1 as a key player in postprandial glucose regulation

Her doctor determined that McDaniel was among a small subset of people (between about 1% and 3%) who develop allergies to GLP-1 injections