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Description
Semaglutide is increasingly recognized as a key add-on therapy within a multidrug strategy to manage chronic kidney disease (CKD), particularly in patients with type 2 diabetes.

Purpose of Review: This article summarizes the medical management of obesity with an emphasis on incretin-based therapeutics that target the neuro-hormonal basis of obesity.Recent Findings: Medications that mimic the effect of incretins, a group of peptide hormones released in response to nutrient intake that regulate appetite, result in potent and durable weight loss

Superior Glycemic Control: Dramatically improves insulin sensitivity and pancreatic beta-cell function, making it exceptionally effective at reversing insulin resistance

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New Data: Phase 3 TRIUMPH-4 Results (Retatrutide) Eli Lilly just released topline results from the Phase 3 TRIUMPH-4 trial, evaluating the triple hormone receptor agonist retatrutide in patients with obesity and knee osteoarthritis (OA)

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