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This opens the door for generic versions to enter the market

It will be especially important to test brain penetrance in both sexes under conditions of obesity, diabetes, or any other diseases that are indicated for GLP-1 therapeutics and have the potential to alter the BBB

J Clin Psychiatry 2026;87(3):26br16352 Submitted: January 30, 2026

How tri-agonists work for weight loss Tri-agonists are just like co-agonists but with the addition of glucagon receptor agonists

doi: 10.1186/s13048-022-01092-z 319 JohanssonHKLTaxvigCOlsenGPMSvingenT
| DOI: 10.1001/jama.2025.14392 Copyright 2025 by the American Medical Association
