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Similarly, the phase 3 TRIUMPH-3 trial is recruiting patients struggling with overweight or obesity and who also have a history of cardiovascular disease

16 These changes may lower intraglomerular pressure and confer renal protection, with secondary benefits on BP control

Contrave is an oral extended-release medication that contains two active ingredients: bupropion (an antidepressant, also found in the medicine Wellbutrin) and naltrexone (an opioid antagonist)
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This discovery has prompted investigation into whether these medications might offer benefits beyond glucose control, including potential effects on cognitive function and neurodegenerative conditions such as dementia

This difference isnt psychologicalits biological
