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Keywords: Glucagon-like peptide-1 agonists, Osteoarthritis, Rheumatoid arthritis, Psoriatic arthritis, System lupus erythematosus, Inflammation Core Tip: Growing evidence suggests that glucagon-like peptide-1 and its receptor agonists could be an effective treatment option not only for metabolic disorders but also for a range of autoimmune and inflammatory diseases

doi: 10.1111/j.1464-5491.2012.03652.x

Furthermore, an improvement in NAS was observed in 83% of patients treated with semaglutide 0.4 mg/day, 80% of those treated with 0.2 mg/day, 71% of those treated with 0.1 mg/day and only 44% of those treated with placebo

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Moberly SP, Berwick ZC, Kohr M, Svendsen M, Mather KJ, Tune JD: Intracoronary glucagon-like peptide 1 preferentially augments glucose uptake in ischemic myocardium independent of changes in coronary flow

Most people start with 1 capsule a day and increase as needed