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The role of GLP-1 in the nervous system largely, but not exclusively, complements peripheral actions of this peptide and encompasses suppression of food and water intake and the reduction of appetite and food reward

[6] [35] In May 2026, the CHMP adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Liraglutide Stada, intended for the treatment of insufficiently controlled type 2 diabetes

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3 and Supplementary Table 3)

Our data also document changes in other specific hypothalamic signaling pathways that may be related to the metabolic effects of the multi-agonist, as is the case of calcium/calmodulin-dependent protein kinase 2 (CAMK2)

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