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Accessed January 2026

While Retatrutide wins on paper, Zepbound wins in the real world for a few key reasons: *The options weve highlighted as the winner are based on the evidence currently available

Research shows that 25-40 grams of protein per meal effectively stimulates L-cell GLP-1 secretion

Protein intake plays a key role in hair health, and people losing weight on GLP-1 medications may need more protein to support both hair and muscle

How to administer retatrutide Like other injectable medications in its class, retatrutide is administered just under the skin (subcutaneously) once a week

Agonists activate the same cell receptors as the body's natural chemical messengers
