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How much of the metabolic effect is central vs peripheral

While semaglutide GLP-1 is highly effective, it is important to address potential gastrointestinal side effects, such as nausea and diarrhea, which are generally transient and manageable

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According to McKinseys analysis, 61% of GLP-1 patients seeking aesthetic treatment had lost 11-30% of their body weight, highlighting how significant weight reduction directly correlates with the desire for surgical skin removal

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