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Decara J, Rivera P, Arrabal S, Vargas A, Serrano A, Pavn FJ et al (2018) Cooperative role of the glucagon-like peptide-1 receptor and 3-adrenergic-mediated signalling on fat mass reduction through the downregulation of PKA/AKT/AMPK signalling in the adipose tissue and muscle of rats

53 In SELECT, semaglutide reduced SBP across all baseline categories, with reductions ranging from 2.9 mm Hg in participants without hypertension to 3.7 mm Hg in those with stage 2 hypertension, without a marked increase in effect among higher baseline BP groups

Primary Handling editors: Jennifer Sargent and Jerome Staal, in collaboration with the Nature Medicine team Data availability Lilly provides access to all individual participant data collected during the trial, after anonymization, with the exception of pharmacokinetic or genetic data

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