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Description
Trends Endocrinol Metab 22:2433 Tiano JP, Delghingaro-Augusto V, Le May C et al (2011) Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents beta cell failure in rodent models of type 2 diabetes
These medications are commonly used for weight management and type 2 diabetes, but their impact can go beyond that
This area can be slightly more difficult to reach by yourself, so it might be helpful if a partner or caregiver is assisting you

Cell biochemistry and function
Increased fat accumulation can lead to inflammation (non-alcoholic steatohepatitis [NASH]) and liver fibrosis, and can further advance to NASH-related cirrhosis, which is the fastest-growing indication for liver transplantation in western countries [10]

Three clinical sites in the United States conducted this trial, starting in August 2020 and completing in November 2022
