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Eli Lilly) have been propelled to the forefront of both medical innovation and public discussion. The surging demand for GLP-1s, fuelled in part by social media amplification and celebrity endorsement, has collided with constrained []

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Health Canada says unauthorized versions of glucagon-like peptide-1 (GLP-1) receptor agonist drugs, are appearing for sale both online and in stores across Canada

--- Here are some potential actions covered in the article for payers and employers to take as a result of this shift: Update formulary tiers and step therapy policies (consider the impact on comorbidities) Support members transitioning off GLP-1s after reaching their goals Create differentiated access pathways based on patient risk profiles Monitor realworld outcomes beyond A1C (cardiovascular, renal, adherence) Model the downstream impact on generics and legacy therapies --- Commercial plans are accelerating GLP-1 uptake and favoring the simplicity of a single therapy