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Beyond the immediate controversy, the rise of compounded GLP-1s reveals a structural shift in how healthcare demand is being met in the United States
Tirzepatide treatment was administered at three final doses (5, 10, 15 mg per week), with treatment initiated at 2.5 mg and the dose escalated every 4 weeks

However, safety concerns have persisted for years regarding the pancreatic effects of GLP-1 RAs
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Sanyal AJ, Kaplan LM, Frias JP, et al

The primary outcome (the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke) was less frequent in the liraglutide group (13.0% vs
