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Stimulation of the hypothalamic arcuate nucleus increases brown adipose tissue nerve activity via hypothalamic paraventricular and dorsomedial nuclei

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A pilot study (study 3: 0.3 and 3 mg/kg, orally once daily) and a complete varied dose study (study 4: 0.1, 0.5, 2.5 and 12.5 mg/kg, oral once daily) in ob/ob for 30 days

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Adv Ther (2013) 30:81101

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GLP-1 receptor agonist cessation While cessation of GLP-1 RA treatment is associated with marked weight regain, whether repeated GLP-1 RAs treatment and subsequent weight regain increases the risk for sarcopenia or sarcopenic obesity remains unknown

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Glapp users are self-selectedpeople who use a tracking app may already be more motivated than typical GLP-1 patients

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pmid:33161163 13

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