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This allows ubiquitination and degradation of phosphorylated JAK1, terminating STAT5 activation ( Figure 2 )

GPR119 agonists increase GLP-1 secretion (29) and GPR119 knockout mice have a reduced GLP-1 response to an oral glucose load (132)

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The study of Hall ( in vitro experiments, which should be further evaluated in future studies

Chen C, Li S, Zhou Y, Huang H, Lin J-T, Wu W-F, et al

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