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PMID: 16484611 DOI: 10.1161/01.RES.0000214553.37930.3e Fitzgerald DJ, FitzGerald GA (2013): Historical lessons in translational medicine

TL;DR: Whole-Body Benefits Microdosing impacts more than just body weight: Better insulin sensitivity at the cellular level through blood glucose management Reduced liver fat and improved liver enzyme profiles Lower inflammation inside blood vessels Slower decline in kidney function and improved eGFR Less neuroinflammation and stronger blood-brain barrier Calmer, less hyperactive immune responses Microdosing vs Full Dosing Choosing between microdosing and full dosing depends on goals, side effect tolerance, and what you are realistically willing to stick with
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