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Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a class of medications originally developed for type 2 diabetes and, more recently, obesity treatment

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Key Takeaways Different FDA Approvals : Wegovy is FDA-approved specifically for chronic weight management in adults with obesity (BMI 30) or weight-related conditions (BMI 27), while Ozempic is FDA-approved only for type 2 diabetes management

Mounjaro/Zepbound (tirzepatide) participants lost an average of 22.5% (52 pounds) of their body weight after 72 weeks

doi: 10.1016/S0006-3223(99)00041-4 164 RajkowskaG.OdwyerG.TelekiZ.StockmeierC