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At 12 months post-GLP-1RA-initiation, the concomitant use of anti-diabetes agents was as follows: metformin, SGLT2 inhibitors, insulin, sulfonylureas, -glucosidase inhibitors, glinides, and thiazolidinediones ( Table 2 )

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Safety: GI events remain the class effect

Hence, similar to semaglutide, the model predicts that patients retain roughly 75% of their weight loss when merely switching from q1wk to q2wk dosing

Effect of insulin-regulated FOXC2 expression in adipocyte differentiation and insulin resistance
