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In 1902 they discovered in anaesthetised dogs that a chemical messenger secreted by the intestinal lining into the bloodstream helped to stimulate the pancreas to produce digestive juices whenever food or acid was introduced into the duodenum

Major guidelines recommend GLP-1RAs as first-line therapy in patients with T2D who have, or are at high risk for, atherosclerotic cardiovascular disease, chronic kidney disease (CKD), or obesity

Greco EV, Russo G, Giandalia A, et al

You need to learn how to hold the vial with your index finger, middle finger and thumb, so, again, I highly recommend checking out our video listed above
Available from: www.dtu.ox.ac.uk/tecos [accessed 3 April 2011]