restarting semaglutide after 3 weeks Just restarted 2 months off and 17 pound regain - Pics don't lie- leg edema 1 week I restarted Wegovy after 7

Medical Weight Loss With Skilled Guidance

doi: 10.2147/DMSO.S272802

In metabolic conditions such as diabetes, prolonged hyperglycemia can damage small nerve fibers through multiple pathways including oxidative stress, accumulation of advanced glycation end products, and microvascular insufficiency affecting nerve blood supply

Reduced gastrointestinal motility throughout the digestive tract prolongs the period during which nutrient sensors in the gut wall send satiety signals

Still the age old calories in and calories out!

16 , 23 To date, there is only one published study examining realworld body weight change outcomes of patients with overweight or obesity treated with semaglutide 2.4 mg