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12-hour light and 12-hour dark cycles) with free access to standard chow (63) or high-cholesterol diet when relevant

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After SLZ injection, the number of positive cells in the submucosa dramatically reduced (Fig

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Subsequently, these two groups independently reported that the synthetic GLP-1 peptide acted as a potent stimulator of insulin secretion in isolated perfused rat pancreas (24) and isolated perfused pig pancreas (23), respectively, thus implicating GLP-1 as the second incretin