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Even a small DVT that breaks loose can sometimes be fatal

Animal studies and pharmacokinetic modeling suggest minimal systemic absorption following oral exposure, but human breastfeeding safety data does not exist

The weight loss attributable to lean mass reported here is less than what is reported in humans, and this could be due to a number of factors including: differences in starting body composition in a human vs mouse, species specific differences in metabolic rates, drug concentrations, and dose scheduling

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J., Rosenstock, J., Sesti, G., krha, J., Khunti, K., & et al

Monitoring heart rate during treatment is recommended