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Severe kidney disease or dehydration risk GI side effects can lead to dehydration and, in vulnerable patients, acute kidney injury

Hypothalamus and released from the posterior pituitary Pituitary A small, unpaired gland situated in the sella turcica

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In patients with moderate ASCVD risk and hypertension, LDL-C-lowering drug therapy should be considered if LDL-C levels are 2.6 mmol/L, alongside lifestyle modifications