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This effect is exactly what makes these medications potentially dangerous for people with eating disorders

Since either metformin or GLP-1 analogue has vascular protective effects 7,24 , we reasonably hypothesized that this combination therapy might also have a synergistic protective effect on endothelial function

Endoscopic Sleeve Gastroplasty (ESG) Endoscopic Sleeve Gastroplasty is a procedure that uses a flexible tube called an endoscope to reshape your stomach, making it smaller and less able to hold large amounts of food

Pending those results, some authors in the literature have advocated for early prophylactic intervention for levels of retinopathy that approach current evidence-based treatment thresholds

Table 1 provides a general clinical comparison of these medication classes for the treatment of T2DM