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The risk of hypoglycemia was low, and the most common adverse events were gastrointestinal, with nausea and diarrhea generally being the most frequently reported manifestations

However, the long-term effects on a patients health beyond the trial timelines and on the costs to the healthcare system are uncertain.

Common (mild) side effects: Nausea, vomiting, stomach pain, diarrhea or loose stools, headache, and fatigue are among the more frequent side effects

Their dual mechanism may address key limitations of current pharmacotherapies