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Aims/hypothesis Regulators worldwide are reviewing safety data on glucagon-like peptide-1 receptor agonists (GLP-1RA), following reports by the Icelandic Medicines Agency in July 2023 of suicidal ideation and self-injury (SIS) in individuals taking liraglutide and semaglutide

Bad breath can develop during GLP-1 therapy, but it's usually manageable with simple oral hygiene adjustments

GLP-1 medications are now accessible at prices below $150 per month through PlexusDx, which offers compounded semaglutide and tirzepatide from licensed 503A pharmacies without insurance requirements

Assumptions on how long diabetes is prevented: four years (which comes from tirzepatide clinical trials) vs

EU recommends updating Wegovy (semaglutide 2.4 mg) label to reflect reduced heart failure symptoms and improved physical function in obesity-related HFpEF, following positive STEP HFpEF trials