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However, these benefits must be balanced against possible side effects of fluid retention and congestive HF [196, 197, 202], weight gain [196,197,198, 202, 203] and bone fracture [204, 205]

Therefore, an array of small peptide linkers was tested

We emphasize that SYGL-1 and LST-1 must also have FBF-independent functions, because the lst-1 sygl-1 phenotype is more severe than the fbf-1 fbf-2 phenotype [15, 18], and because single sygl-1 and lst-1 mutants enhance the fbf-1 fbf-2 phenotype [25

But, this side effect can be avoided by following a few best practices before, during and after the injections

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