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van Kleef, MD, PhD, and colleagues asked the next question, which is the more practical one

More serious risks include pancreatitis, gallbladder disease, acute kidney injury from dehydration, and hypersensitivity reactions

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When protein intake is insufficient, the body may break down muscle tissue for energy, which can result in: Weakened muscles and reduced strength A slower metabolism, making calorie burning less efficient An increased risk of regaining weight after stopping the medication Additionally, research suggests that GLP-1 therapy decreases muscle protein synthesis, meaning the body has a harder time rebuilding lost muscle

doi:10.1038/s41392-024-01951-9 Uusitupa M, Khan TA, Viguiliouk E, et al

These reports could be preprints, journal articles of the main results, and post hoc analyses [17]