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Behavioral strategies proven effective for weight maintenance include consistent self-monitoring of weight (at least weekly), food logging, regular meal patterns, and cognitive behavioral techniques to address emotional eating and environmental triggers

Consider separating eating and drinking

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In summary, these strategies support the preservation of lean mass, functional capacity, and safety in older adults, while enabling the mitochondrial, metabolic, and broader healthspan-supporting benefits of GLP-1 RAs

The important takeaway is that retatrutide does not appear significantly worse for fatigue than its predecessors, despite activating an additional receptor pathway (glucagon)

Adding B12 to this treatment enhances the metabolic effect, ensuring that the body maintains energy and nerve function during the weight loss journey