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GLP-1 is produced through the proteolytic processing of proglucagon, promoting insulin secretion while inhibiting glucagon production

Most clinical guidance recommends: At 3 months: A1c recheck (HbA1c reflects the prior 3-month average, making this the earliest timepoint for meaningful assessment of glycemic response), metabolic panel if any GI side effects were significant At 6 months: Full panel repeat A1c, CMP, lipids, CBC to document treatment response comprehensively Annually: Full panel plus thyroid function, B12, and any additional markers relevant to your individual health picture If you experience severe or persistent gastrointestinal side effects, signs of dehydration, unusual fatigue, or any concerning symptoms, kidney function should be rechecked without waiting for a scheduled interval

Stomach paralysis can result from various factors but is a documented side effect of taking GLP-1 and similar drugs like Ozempic and Mounjaro

At steady state, the amount entering your body equals the amount being eliminated

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It is also prescribed in combination with physical exercise and diet or alone