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This review explores the complex interplay between hyperkalemia and the use of guideline-directed medical therapies (GDMT), such as reninangiotensinaldosterone system inhibitors (RAASi) and steroidal mineralocorticoid receptor antagonists (sMRAs), including spironolactone and eplerenone, which are currently recommended in guidelines for improving outcomes in heart failure with reduced ejection fraction (HFrEF)

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Phase 2 trial results suggest retatrutide may offer a triple therapy option to address the multiple metabolic factors that affect people who are obese, regardless of type 2 diabetes status, said Arun J

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A new study shows the obesity drug Wegovy improved function in patients with a common type of heart failure and diabetes, setting the stage for even broader use of the drug.

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