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However, largescale pharmacoepidemiologic studies have not demonstrated a statistically significant association to date

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The fact that retatrutide passed its Phase 1 and Phase 2 trials means researchers deemed it safe enough for large-scale human testing
Factors associated with response to GLP-1 RA treatment Older adults and GLP-1 RA treatment response In elderly patients with overweight or obesity with T2DM, Perna et al