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Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses

Monocytes transform into macrophages, which are involved in the inflammatory reaction

In this small study, nausea was very common and one patient withdrew due to diarrhea

13.8%: Broad eligibility + perfect adherence 10.4%: Broad eligibility + real-world adherence 8.1%: Narrow eligibility + perfect adherence 6.1%: Narrow eligibility + real-world adherence Even with cost-sharing (e.g., $90 copay), premium increases only drop by 12 percentage points

Statements Author contributions IZ, MP, GA, FG, VC, AS, and FA participated in the study conceptualization

Weeks 13 to 16: Reduce from 0.5 mg to 0.25 mg weekly