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Description
The concept of permanent metabolic damage has been largely debunked by controlled research, though it remains a persistent myth in weight loss communities

Participation in a properly regulated trial is currently the only legitimate route through which a patient in the UK might access this medication

See the pooled clinical-trial evidence here

Obesity-resistant mouse lines show increased brown adipose tissue thermogenesis and GLP-1 production
Others lose weight initially and then regain some or all of it, particularly if insurance coverage lapses or the medication becomes unattainable

PMID: 2 Abu-NejimH.BeckerR
