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The most commonly reported adverse events in SURMOUNT-3 were gastrointestinal-related and generally mild to moderate in severity

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Real-world nausea rates are likely higher, which means the relative benefit of microdosing may be larger than these trials suggest

Compounded medications are custom-made based on a patient's prescription

Lilly has repeatedly warned that compounded tirzepatide products carry serious safety risks including dosing errors, contamination, and inactive ingredients and the FDA ended the shortage-based exception for compounded tirzepatide in early 2025

It improves beta-cell function in the pancreas