glp 1 agonist medullary thyroid cancer GLP-1 receptors (GLP-1R) are expressed in premalignant lesions in human More Thyroid Cancers Found After
Description
Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells

Strategies to correct the incretin defects in patients with type 2 diabetes include replacement of GLP-1 with a long-acting analog that resists degradation and development of drugs that inhibit the enzyme DPP-4, which breaks down GLP-1
Nature 499 , 444449 (2013) Jazayeri, A

For most researchers, yes, though they require more active management than tirzepatide side effects

Pancreatitis associated with the use of GLP-1 analogs and DPP-4 inhibitors: a case/non-case study from the French Pharmacovigilance Database

Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain