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Description
The most recent International Diabetes Federation (IDF) report estimates that 425 million adults worldwide (8.8% of the global population) have diabetesa number that is projected to increase to 629 million by 2045 [6]

Looking back, those were early clues that GLP- 1 receptor agonists cause food aversion

This highlights the need for identifying novel pharmacological interventions

Anti-exenatide antibodies were detected in 40%-60% of clinical patients

In the pancreas, the interaction of GLP-1 and GLP-1R is known to mainly act through the cAMP-PKA pathway

21 Alcohol: Can worsen nausea, potentially interact with the medication's effects on blood sugar or the liver, and contribute to dehydration
