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If you suspect an adverse reaction to a GLP-1 medication, report it to the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

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This helps dilute urine and prevents crystal formation, particularly if you experience gastrointestinal side effects

European Academy of Dermatology and Venereology Congress, Paris, France

In a later interview with People , published in December 2025, Winfrey revealed that just six months after starting GLP-1s, shed decided to see if she could beat the medication by stopping taking them