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It alters brain chemistry by inhibiting the reuptake of dopamine, norepinephrine, and serotonin the same neurotransmitters that regulate appetite, reward, mood, and energy

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The main tradeoff is higher cost

This persistent tiredness doesnt go away with sleep and can significantly impact your daily energy levels and overall well-being

Semaglutide is a glucagon-like peptide 1 (GLP-1) receptor agonist used to improve blood sugar control in adults with type 2 diabetes

The appetite-suppressing effects mediated through GLP-1 and GIP receptor activation diminish as the medication clears from the system, with most of the drug eliminated within 3-4 weeks (approximately 4-5 half-lives)