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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Strong J, Driscoll MS

This is particularly important, as individuals with a history of self-harm or suicidal ideation could be most vulnerable to adverse psychiatric events related to GLP-1 receptor agonist use

Additionally, as in cell cultures, liraglutide suppressed CD36 and ACAT1 expression in macrophages but did not affect ABCA1 expression

Even more telling, gastrointestinal side effects causing treatment discontinuation were lower with tirzepatide (2.7%) than semaglutide (5.6%)

More severe reactions could include difficulty breathing, swelling of the face, lips, tongue, or throat, which would require immediate emergency medical treatment