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In contrast, more than 80% of those starting SGLT2 or insulin added another medication

Currently available only within Phase 3 clinical trials, retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from approved therapies such as semaglutide and tirzepatide

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Injection Sites: Inject into the fatty tissue just under the skin in the abdomen, front thigh, or outer upper arm

The bigger picture: retatrutide in the bodybuilding landscape GLP-1 agonists have fundamentally changed how bodybuilders approach cutting phases